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時間:2022-08-16 來源:本站 點擊:258次

First woman cured of HIV after stem cell transplant******

A US patient with leukemia hasbecome the first woman and the third person to date to be curedof HIV after receiving a stem cell transplant from a donor whowas naturally resistant to the virus that causes AIDS,researchers reported on Tuesday.

The case of a middle-aged woman of mixed races, presented atthe Conference on Retroviruses and Opportunistic Infections inDenver, is also the first involving umbilical cord blood, anewer approach that may make the treatment available to morepeople.

Since receiving the cord blood to treat her acute myeloidleukemia – a cancer that starts in blood-forming cells in thebone marrow – the woman has been in remission and free of thevirus for 14 months, without the need for potent HIV treatmentsknown as antiretroviral therapy.

The two prior cases occurred in males – one white and oneLatino – who had received adult stem cells, which are morefrequently used in bone marrow transplants.

"This is now the third report of a cure in this setting, andthe first in a woman living with HIV," Sharon Lewin,president-elect of the International AIDS Society, said in astatement.

The case is part of a larger US-backed study led by Dr Yvonne Bryson of the University of California Los Angeles(UCLA), and Dr Deborah Persaud of Johns Hopkins University inBaltimore. It aims to follow 25 people with HIV who undergo atransplant with stem cells taken from umbilical cord blood forthe treatment of cancer and other serious conditions.

Patients in the trial first undergo chemotherapy to kill offthe cancerous immune cells. Doctors then transplant stem cellsfrom individuals with a specific genetic mutation in which theylack receptors used by the virus to infect cells.

Scientists believe these individuals then develop an immunesystem resistant to HIV.

Lewin said bone marrow transplants are not a viable strategyto cure most people living with HIV. But the report "confirmsthat a cure for HIV is possible and further strengthens usinggene therapy as a viable strategy for an HIV cure," she said.

The study suggests that an important element to the successis the transplantation of HIV-resistant cells. Previously,scientists believed that a common stem cell transplant sideeffect called graft-vs-host disease, in which the donorimmune system attacks the recipient's immune system, played arole in a possible cure.

"Taken together, these three cases of a cure post stem celltransplant all help in teasing out the various components of thetransplant that were absolutely key to a cure," Lewin said.

西安女子在西旅逸都买的新房漏水 一年多没找到原因******









10日晚上,华商报记者了解到,10日下午,物业已联系施工人员前往常女士的家里,对漏水原因进行检查。 华商报记者 卿荣波



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Chinese war epic "The Battle at Lake Changjin" hits North American big screen******

LOS ANGELES, Nov. 19 (Xinhua) -- The Chinese war epic "The Battle at Lake Changjin" opened Friday in a limited theatrical release in North America.。

The film is being released by CMC Pictures with English subtitles in more than 20 selected theaters in Los Angeles, San Francisco, New York, Boston, Dallas, Seattle, Vancouver, Toronto and a few other cities across North America.。

Jointly directed by Chen Kaige, Hark Tsui and Dante Lam, the film is set in the winter of 1950 during the War to Resist U.S. Aggression and Aid Korea. Faced with the harshest conditions of extreme cold, lack of rations and vast difference in weaponry, Chinese People's Volunteers (CPV) soldiers forge ahead, fearless and determined in a key campaign at Lake Changjin, or Chosin Reservoir.。

"I didn't expect to see the film in the United States. It's a powerful war epic, which can touch the audience," a moviegoer who only gave his surname as Li told Xinhua after the movie Friday afternoon in an AMC theater in Monterey Park, Los Angeles County.。

"History tells us a lot and make us cherish peace," he added.。

"The Battle at Lake Changjin" is the highest-grossing film worldwide so far this year, having grossed a massive 5.668 billion yuan (886 million U.S. dollars) in the Chinese mainland alone since Sept. 30, according to the box office data compiled by Maoyan, a Chinese movie-ticketing and film data platform.。

It's also the second-highest-grossing title of all time at China's box office, trailing only the 2017 Chinese action film "Wolf Warrior 2," which earned 5.69 billion yuan (890 million dollars). Enditem。

Premier League to meet as Covid wrecks havoc with weekend fixture list******

LONDON, Dec. 18 (Xinhua) -- The Premier League clubs are expected to meet on Monday to discuss whether or not the competition should continue or take a break after a weekend in which six of the 10 scheduled matches have had to be postponed due to outbreaks of Covid-19 at several clubs.。

Saturday's match between Burnley and Aston Villa was the latest to fall victim to the virus and was cancelled just two and a half hours before the scheduled 15:00 hours kick off after further cases of the virus among the visitors' squad.。

"After reviewing all the new information provided by Aston Villa this morning and receiving separate medical advice, the board approved the request as a result of the club not having enough players to field a team. This decision was based on the number of Covid-19 cases, injuries and illness," explained a statement issued by the Premier League.。

Matches between Manchester United and Brighton, Southampton and Brentford, Watford and Crystal Palace, West Ham and Norwich and Everton and Leicester had all previously fallen by the wayside because of outbreaks at various clubs.。

Meanwhile the matches between Newcastle United and Manchester City, Wolves and Chelsea, as well as Tottenham and Liverpool are still scheduled for Sunday, although with Liverpool and Chelsea also reporting cases of Covid-19, there is still time for that to change.。

"The board assesses applications to postpone matches on a case-by-case basis, based on existing rules and Covid-19 postponement guidance issued to all clubs."

"It will assess a number of factors, including the ability of a club to field a team; the status, severity and potential impact of the Covid-19 outbreak at the club; and the ability of the players to safely prepare for and play the match. The board must also consider the wider risks to the opposition and other people the club representatives may come into contact with," said the Premier League, who added that new protocols, which include "more frequent testing, wearing face coverings while indoors, observing social distancing and limiting treatment time," have all introduced.。

In Saturday's surviving game Arsenal piled the pain onto Leeds United with a 4-1 win in Elland Road.。

The game was as good as over at halftime as two goals from Gabriel Martinelli and one from Bukayo Sako put Arsenal 3-0 up and although Raphinha scored a 75th minute penalty for Leeds, Emile Smith Rowe rounded off a good afternoon for Arsenal with five minutes left to play.。

Next weekend is one of the most important of the Premier League, with the traditional Boxing Day games quickly followed by a midweek game and a round of New Year fixtures. Enditem。

长征五号 B 遥四运载火箭通过出厂评审,将送“梦天”


2.意甲-天使建功弗拉霍维奇梅开二度 尤文3-0萨索洛



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